Showing posts with label cloning. Show all posts
Showing posts with label cloning. Show all posts

Tuesday, July 18, 2006

Aborting Reason to Justify Killing

An excerpt from a NY Times editorial supporting the expansion of federal funds for embryonic stem cell research (my comments in italics):

"Therapeutic cloning involves the creation of embryos genetically matched to patients with specific diseases so that scientists can extract their stem cells and then study how the diseases develop and how best to treat them. The microscopic entities used in these studies may be called embryos but they have none of the attributes of humanity and, sitting outside the womb, no chance of developing into babies. "

None of the attributes of humanity? These embryos exhibit all the attributes of humanity at the embryonic stage of human development. By the Times' own admission, the embryos in question are clones, genetically matched to human patients. So how can they turn around and say that they have none of the attributes of humanity? To assert both that the embryos are human clones and that they are void of any of the attributes of humanity is to assert a contradiction.


What the editors really mean is that human embryos don't look like more mature humans. But this is no justification for killing them.

Monday, July 03, 2006

Non-scientific Motivations: James Sherely on Harvard's Stem Cell Plan

A few weeks ago I pointed to a Boston Globe editorial by M.I.T. biological engineer and Harvard graduate James Sherley in which he criticized Harvard's plan to attempt human embryo cloning for stem cell research on scientific and ethical grounds. In a recent interview with MercatorNet (HT: Mere Comments), he gives more reasons for his opposition and asks the most critical question. Some excerpts:

MercatorNet: As a world-renowned university, Harvard prides itself on the calibre of its cutting-edge academics, not only in science, but also ethics, theology and politics. But has the desire to maintain Harvard's reputation affected its ethical judgement?

Sherley: The public should demand to hear this question addressed by Harvard professors of ethics, politics, history of science, and economics and also by Harvard professors who have a dissenting view. They may be silent, muted, or unreported on the issue. The public needs to know which is the case. Surely, this revered faculty of original and independent thinkers, who recently cast out their President for his regressive prejudicial ideas, is not monolithic in its view on the moral status of human embryos and their treatment by Harvard scientists.

MercatorNet: You seem pretty convinced that human embryos are human beings. Can you explain briefly why?

Sherley: My answer is, "What else could they be -- aliens?" Scientists who want to conduct experiments with human embryos are quick to say what human embryos are not. I challenge them to tell the public what human embryos are. There is only one answer to this question, "living human beings."

MercatorNet: But why can't you convince your colleagues at Harvard and MIT of your point of view? What's the stumbling block?

Sherley: When scientists arrange their own press conferences to announce promises for the future that involve significant self-gain, let the public beware. The stumbling block is non-scientific motivations.
I encourage you to read the whole thing. And if you'd like to read my reaction to Harvard's stem cell initiative, I blogged about it here.

Tuesday, June 13, 2006

A Horrifying Vision

James Kelly, biotech writer for The Seoul Times, explains what changed his mind about backing embryonic stem cell research:

In 2002 I changed my stem cells course because of a horrifying vision – the image of millions of desperate and trusting humans holding plates of hope to an empty sky.
The actions of scientists have confirmed my course. While telling the American people that they only want "to keep all research options open," science and industry convinced the people of California to commit three billion dollars to ES cell research and human cloning – ten times the annual NIH budget for adult stem cell research. They're pursuing an additional billion dollars in public funds in both New York and Illinois, and another $750,000,000 from Wisconsin.  Under the guise of "keeping all options open," colossal resources are being siphoned away from practical and foreseeable causes for medical hope.
Kelly, who has testified before Congress and debated the late Christopher Reeve, has been paralyzed since 1997 and is Director of the Cures 1st Foundation in the US. His article reveals numerous ways that the public is purposefully misinformed and misled by backers of embryonic stem cell research. Here's an example:
One Washington-based science reporter, an avowed atheist, often writes that embryonic stem (ES) cells "can become every cell in the body." But he fails to mention that nine months of fetal development in the fetus are needed to do this. Nor does he report that ES cells matured in vitro (in a petri dish) tend to be genetically unstable and often function abnormally. Yet issues such as these determine whether publicly funded science leads to medical treatments in a foreseeable future, in a decade or two, or never.
Kelly has come to the conclusion that embryonic stem cells are of little practical worth for therapeutic purposes and gives ample support for his position. His thoughtful article should lead us to question who is really being anti-scientific and dispassionate. (HT: stem-cell-therapy.blogspot.com)

Thursday, June 08, 2006

Veritas? Harvard's Stem Cell Initiative

Last night I read a press release announcing Harvard University's launch of a privately funded program that will create cloned embryos for the purpose of embryonic stem cell research. I wondered how the institution would handle the ethical controversy surrounding the procedure so I read this article in the Harvard Gazette. Doing so left me thinking how ironic it is that the school's seal bears the Latin word for "truth."

Consider the following quote from Lawrence Summers, Harvard's president:

While we understand and respect the sincerely held beliefs of those who oppose this research, we are equally sincere in our belief that the life-and-death medical needs of countless suffering children and adults justifies moving forward with this research.
Notice, Summers didn't identify the beliefs he claims to understand and respect. Nor did he attempt to offer any reasons why those beliefs are false. He, like many other backers of embryonic stem cell research simply evaded the issue of greatest importance - the moral status of the human embryo.

What's more troubling, however, is that a leader of a renowned intellectual center would suggest that the sincerity with which one holds a belief is sufficient warrant for holding it. Instead of offering a rational justification for Harvard's actions, Summers essentially says, "We're as convinced that we are right as our opponents are that we're wrong." So much for debate and moral discourse. What kind of example is Summers giving Harvard's young scholars when he engages in this kind of rhetoric?

Douglas Melton, co-director of the Harvard Stem Cell Institute didn't fare any better in his attempt to address the ethical issue:

But Melton responds that "all human cells, even individual sperm and eggs, are 'living.' The relevant question is 'when does personhood begin?' That's a valid theological or philosophical question, but from the scientific perspective, this work holds enormous potential to save lives, cure diseases, and improve the health of millions of people. The reality of the suffering of those individuals far outweighs the potential of blastocysts that would never be implanted and allowed to come to term even if we did not do this research," he said.
Melton tries to blunt the force of the fact that harvesting an embryo's stem cells inevitably results in its death by likening it to any other somatic cell. But this is misleading. Yes, it's true that human cells are alive but the crucial difference between an embryo and a sperm or egg cell is that the embryo is a complete human being - not simply a part. In order to escape this, Melton evokes the artificial distinction between a human being and a person, saying that this is the relevant question. The inescapable conclusion of reasoning like Melton's is that human life has no inherent value. It is whatever qualities he thinks a human being must possess in order to qualify as a person that are actually valuable. And, of course, this has troubling consequences for more members of our species than just the preborn.

If you pay careful attention to Melton's comments, you'll also note the frequently observed attempt to trump philosophy and theology with science. Sure, philosophy and theology may ask some valid questions but they don't deal with reality like science does. Melton contrasts the philosophical/theological issue of when personhood begins with the scientific fact (?) that embryonic stem cell research holds great potential for finding cures for millions. Improving the lives of this number outweighs the cost of destroying nascent individuals. But note that this is not a scientific but an ethical (and thus, philosophical) assertion.


I'm thinking Harvard needs a new seal...again.

Friday, February 17, 2006

A Clone by Any Other Name

Someone in our congregation emailed me requesting information about the ethical issues related to stem cell research. One of his coworkers has been absent from work due to cardiac complications and his fellow employees are trying to raise money for him to undergo treatment that involves stem cells of some sort. To his credit, the gentleman in our church wanted clarification before he made a contribution. This request serves as a vivid reminder of why it's important for Christians to be aware of the ethical issues that accompany advances in medical technology. The following is an edited excerpt from my reply:

Before I made a financial contribution toward stem cell therapy, I'd want to know what kind of stem cell treatment is involved.

There are two methods for acquiring these cells which have the unique ability to transform into various kinds of tissue. The ethically controversial method involves harvesting the desired cells from human embryos produced by cloning or provided by fertility clinics (embryos created for the purpose of reproduction but no longer wanted by their parents).

What's referred to as therapeutic cloning requires taking a female egg, removing its nucleus, and replacing it with the genetic material of the person to be treated. By means of electrochemical stimulation, this cell begins the process of cellular division and is essentially an embryonic clone of the donor. Given the proper environment it would progress through the stages of maturation as would any other embryo.

Advocates of this method refer to it as therapeutic cloning because it involves the cloning of an individual in order to potentially cure him or her of a disease. Proponents contend that while it would be unethical to allow this embryo to come to full term (reproductive cloning), it's morally acceptable to destroy it in its earliest stages in order to benefit others suffering from various diseases. However, this is merely to justify taking some human lives in order to improve others.

In contrast to embryonic stem cells, adult stem cells are produced in various parts of our bodies and can be obtained without taking human life. I would have no problem supporting therapy involving these.

For more information about stem cell research, I encourage you to read an article offered by the Center for Bioethics & Human Dignity called "Stem Cell Research and 'Therapeutic' Cloning: A Christian Analysis." It's written in a Q & A format and isn't very long. It will not only help you to make an informed decision about your participation in this situation but will also serve to equip you to confidently engage your coworkers on this important topic.
In an op-ed piece in yesterday's New York Times, Michael Gazzaniga, the director of Dartmouth's Center for Cognitive Neuroscience and a member of the President's Council on Bioethics, castigates President Bush for requesting that Congress "pass legislation to prohibit the most egregious abuses of medical research: human cloning in all its forms." Gazzaniga takes issue with the President's referring to both therapeutic (or what he calls "biomedical") and reproductive cloning as egregious abuses. While he presumably thinks that such a description is fitting for the former kind of cloning, he finds it completely inappropriate for the latter. President Bush's characterization "makes it sound as if the medical community is out there cloning people, which is simply not true." Oh?

You'll have to read Gazzaniga's article for yourself but I find it quite confusing and contradictory. On one hand he denies that scientists are cloning people while acknowledging that both the products of reproductive and biomedical cloning are.....clones! For crying out loud, the article's title is "All Clones Are Not the Same!" If, as Gazzaniga claims, medical researchers are not cloning people, one wonders what exactly is being cloned? He writes that "the phrase 'in all its forms' is code, a way of conflating very different things: reproductive cloning and biomedical cloning." But in actuality, what makes reproductive and biomedical cloning differ is not the product or process but the intent of those doing the cloning. Concerning the oxymoron of so-called therapeutic cloning, Amy Coxon notes:

...there is absolutely no difference in the scientific techniques used to accomplish - or the embryonic human beings produced - via therapeutic cloning or the cloning of a human being for other purposes. The idea that an "organism" created by cloning is a "new type of biological entity never before seen in nature" is an attempt by scientists to hide the truth of this new technology behind scientific jargon. Instead of calling this cloned organism an embryo, which is precisely what it is, scientists have labeled it an "activated egg." This is again manipulation of terminology with the hope of deceiving the public. In fact, the term "therapeutic cloning" itself is used to deceive the general public into believing that human cloning is acceptable and beneficial in certain medical circumstances. With the media's and the scientific community's frequent misuse of scientific terminology, it is crucial that we as Christians correctly discern the meanings behind this terminology. If we do not take steps to understand the science, we cannot defend our position in an educated manner and therefore will have no public voice on these issues.
Gazzaniga says that in 2002, he and the other members of the President's Council on Bioethics "voted unanimously to ban reproductive cloning--the kind of cloning that seeks to replicate a human being." He goes on to say that this kind of cloning has not been attempted and is not in the works. But this is misleading. In an attempt to derive embryonic stem cells compatible with a diseased person's system, a procedure known as somatic cell nuclear transfer is performed. This involves replacing the nucleus of an unfertilized egg with a somatic cell from the patient. Cellular division is then stimulated so that eventually stem cells can be harvested from the embryonic clone which is destroyed in the process. Regardless of the absence of intent to allow the clone to mature into subsequent stages, the fact remains that it is a human clone.

If there is anything with which I agree with Dr. Gazzaniga about it's that at the heart of the moral debate surrounding biomedical cloning is a clash of ideas about what it means to be human. According to Gazzaniga, President Bush's concept of what constitutes humanness is "nonsensical" and "a form of the 'DNA is destiny' story."
To the contrary, he asserts, "...all modern research reveals that DNA must undergo thousands if not millions of interactions at both the molecular and experiential level to grow and develop a brain and become a person. It is the journey that makes a human, not the car."

When they're not accusing opponents of embryonic stem cell research of being dispassionate, they're accusing us of being unscientific. However, if you pay close attention to what Dr. Gazzaniga is saying, you'll see that his case does not rest on scientific conclusions but on a functionalist view of humanness or personhood. The distinction that Gazzaniga would like to make is a philosophical not a scientific one. The claim that only those members of the human species that have a brain functioning at a certain level count as human beings or persons is not one that can be verified or falsified by means of empirical inquiry. Furthermore, Gazzaniga's analogy between the earliest stage of human development and a vehicle is faulty. Regardless of how long a drive I take, it will never be true that I was a car. However, it is true that I was once an embryo.

Concluding his essay, Gazzaniga writes:

In his State of the Union speech, President Bush went on to observe that "human life is a gift from our creator-and that gift should never be discarded, devalued or put up for sale." Putting aside the belief in a "creator," the vast majority of the world's population takes a similar stance on valuing human life. What is at issue, rather, is how we are to define "human life." Look around you. Look at your loved ones. Do you see a hunk of cells or do you see something else?
Most humans practice a kind of dualism, seeing a distinction between mind and body. We all automatically confer a higher order to a developed biological entity like a human brain. We do not see cells, simple or complex-we see people, human life. That thing in a petri dish is something else. It doesn't yet have the memories and loves and hopes that accumulate over the years. Until this is understood by our politicians, the gallant efforts of so many biomedical scientists, as good as they are, will remain only stopgap measures.
The tiny cloned embryo in the petri dish may be void of memories, loves, and hopes. But then again, so are newborns. What conclusions would Dr. Gazzaniga have us draw from that?